Lucerastat
CAS No. : 141206-42-0
(Synonyms: NB-DGJ; N-(n-Butyl)deoxygalactonojirimycin)
| Size | Price | Stock |
|---|---|---|
| 5mg | $200 | In-stock |
| 10mg | $350 | In-stock |
| 25mg | $735 | In-stock |
| 50mg | $1250 | In-stock |
| 100mg | $2125 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-106392 |
| M.Wt: | 219.28 |
| Formula: | C10H21NO4 |
| Purity: | >98 % |
| Solubility: | H2O : 24 mg/mL (ultrasonic;warming;heat to 80°C);DMSO : 22 mg/mL (ultrasonic;warming;heat to 80°C) |
Lucerastat, the galactose form of Miglustat, is an orally-available inhibitor of glucosylceramide synthase (GCS). Lucerastat has the potential for Fabry disease study[1][2]. In Vitro:Fabry patient-derived fibroblasts with the genotypes R301G (residual -GalA activity; 20%) R220X (<3%) and W162X (<1%). In Vivo:Lucerastat (1200 mg/kg/day food admix), a GCS inhibitor, reduces Gb3 in the absence of residual-GalA activity[2].
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