TRAP-6
CAS No. : 141136-83-6
(Synonyms: PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6)
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $352 | In-stock |
| 50mg | $540 | In-stock |
| 100mg | $700 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-P0078 |
| M.Wt: | 748.87 |
| Formula: | C34H56N10O9 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic) |
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4[1].
IC50 & Target:PAR1[1]
In Vitro:TRAP-6 (0.01-10 μM) triggers calcium mobilization in Xenopus oocytes heterologously expressing PAR1[1].
TRAP-6 (0.01-10 μM; 30 min) activates human platelets[1].
TRAP-6 (100 μM) does not cause the platelets of rabbits or rats to change shape, aggregate, release granule contents, or form thromboxane[2].
In Vivo:TRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats[3].
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