Royal Jelly acid


CAS No. : 14113-05-4

(Synonyms: (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid)

14113-05-4
Price and Availability of CAS No. : 14113-05-4
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100g $132 In-stock
500g $473 In-stock
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Cat. No. : HY-N1363
M.Wt: 186.25
Formula: C10H18O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 14113-05-4 :

Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases[1][2][3][4][5][6][7]. In Vitro:Royal Jelly Acid (1-4 mM, 24 h) reduces NO production in RAW264.7 cells[3].
Royal Jelly Acid (1-4 mM, 24 h) inhibits IFN-β-induced NF-κB p65 phosphorylation in RAW264.7 cells, suggesting its regulatory role in inflammatory signaling pathways[3].
Royal Jelly Acid (10-100 μM, 24 h) reduces neurotrophic factor expression in Wistar rat cortical astrocytes[4].
Royal Jelly Acid (12.5-100 μg/mL, 72 h) exhibits strong antiplasmodial activity in Plasmodium falciparum K1 strain[5].
Royal Jelly Acid (1-8 μg/mL, 48 h) exhibits antileishmanial activity in Leishmania major amastigotes?[5].
Royal Jelly Acid (1.25-250 μg/mL, 24 h) induces cytotoxicity in MCF-7 breast cancer cells? [7] In Vivo:Royal Jelly Acid (3-6 mg/kg, p.o., once daily for 25 days) significantly inhibits disease progression, reduces inflammatory cell infiltration, and prevents demyelination in the MOG35-55-induced experimental autoimmune encephalomyelitis C57BL/6 mouse model?[6].

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