CAS No. : 14113-05-4
(Synonyms: (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid)
| Size | Price | Stock |
|---|---|---|
| 5g | $7 | In-stock |
| 10g | $14 | In-stock |
| 25g | $33 | In-stock |
| 100g | $132 | In-stock |
| 500g | $473 | In-stock |
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| Cat. No. : | HY-N1363 |
| M.Wt: | 186.25 |
| Formula: | C10H18O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases[1][2][3][4][5][6][7]. In Vitro:Royal Jelly Acid (1-4 mM, 24 h) reduces NO production in RAW264.7 cells[3]. Royal Jelly Acid (1-4 mM, 24 h) inhibits IFN-β-induced NF-κB p65 phosphorylation in RAW264.7 cells, suggesting its regulatory role in inflammatory signaling pathways[3]. Royal Jelly Acid (10-100 μM, 24 h) reduces neurotrophic factor expression in Wistar rat cortical astrocytes[4]. Royal Jelly Acid (12.5-100 μg/mL, 72 h) exhibits strong antiplasmodial activity in Plasmodium falciparum K1 strain[5]. Royal Jelly Acid (1-8 μg/mL, 48 h) exhibits antileishmanial activity in Leishmania major amastigotes?[5]. Royal Jelly Acid (1.25-250 μg/mL, 24 h) induces cytotoxicity in MCF-7 breast cancer cells? [7] In Vivo:Royal Jelly Acid (3-6 mg/kg, p.o., once daily for 25 days) significantly inhibits disease progression, reduces inflammatory cell infiltration, and prevents demyelination in the MOG35-55-induced experimental autoimmune encephalomyelitis C57BL/6 mouse model?[6].
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