NSC5844
CAS No. : 140926-75-6
(Synonyms: RE-640)
| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $110 | In-stock |
| 25mg | $180 | In-stock |
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| Cat. No. : | HY-100033 |
| M.Wt: | 383.27 |
| Formula: | C20H16Cl2N4 |
| Purity: | >98 % |
| Solubility: | DMSO : 1 mg/mL (2.61 mM; ultrasonic and warming and heat to 60°C) |
NSC5844 (RE-640) is a 4-aminoquinoline derivative, with antitumor and antimalarial activity. IC50 & Target: Parasite[2] In Vitro: NSC5844 (Compound 10) is a 4-aminoquinoline derivative, and has antitumor activity with GI50s of 7.35 ± 0.10 μM and 14.80 ± 0.35 μM against MDA-MB-468 and MCF-7 cells, respectively[1]. NSC5844 (Compound 1) is cytotoxic to P. falciparum, inhibits the growth of chloroquine-sensitive (D-6) and -resistant (W-2) clones of P. falciparum, with IC50s of 17 and 27 nM, respectively[2].
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