Hexaminolevulinate (hydrochloride)
CAS No. : 140898-91-5
(Synonyms: Hexyl 5-aminolevulinate hydrochloride; P-1206; 5-Aminolevulinic acid hexyl ester hydrochloride)
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| Cat. No. : | HY-16045 |
| M.Wt: | 251.75 |
| Formula: | C11H22ClNO3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : 100 mg/mL (ultrasonic) |
Hexaminolevulinate (Hexyl 5-aminolevulinate) hydrochloride, a porphyrin precursor, is a photosensitiser that can be used in photodynamic therapy (PDT) for certain tumor. Hexaminolevulinate hydrochloride can improve the visualisation of bladder tumours[1][2].
In Vitro:Hexaminolevulinate (2.5-100 μM; 4 h in serum-free medium) hydrochloride induces PpIX production in L1210 cell line and pure BM[2].
Hexaminolevulinate (1-100 μM; 4 h in serum-free medium) hydrochloride induces PpIX production in the mixtures of BM with L1210 tumor cells[2].
Hexaminolevulinate (20-100 μM) in combination with increasing doses of blue light illumination from 0 to 120 s results in progressive killing of L1210 cells[2].
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