Mangafodipir (trisodium)
CAS No. : 140678-14-4
(Synonyms: MnDPDP)
| Size | Price | Stock |
|---|---|---|
| 5mg | $270 | In-stock |
| 10mg | $435 | In-stock |
| 25mg | $870 | In-stock |
| 50mg | $1390 | In-stock |
| 100mg | $2200 | In-stock |
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| Cat. No. : | HY-B0993 |
| M.Wt: | 757.32 |
| Formula: | C22H27MnN4Na3O14P2 |
| Purity: | >98 % |
| Solubility: | H2O : 33.33 mg/mL (ultrasonic) |
Mangafodipir trisodium (MnDPDP), hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir trisodium shows no negative interference with the tumoricidal activity of chemotherapy[1][2]. In Vitro:Mangafodipir trisodium (40, 200 and 1000 μM) inhibits the effect of HGrC cell viability caused by H2O2[3]. Mangafodipir trisodium (200 and 1000 μM) attenuats the apoptosis caused by cisplatin in HGrC cells[3]. In Vivo:Mangafodipir trisodium (10 mg/kg; i.p., once) shows protective effects against ovarian damage caused by cisplatin and paclitaxel in mice[3].
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