Bacitracin
CAS No. : 1405-87-4
| Size | Price | Stock |
|---|---|---|
| 5g | $42 | In-stock |
| 25g | $147 | In-stock |
| 100g | $486 | In-stock |
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| Cat. No. : | HY-107193 |
| M.Wt: | 1422.69 |
| Formula: | C66H103N17O16S |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
Bacitracin is a polypeptide antibiotic against staphylococcal and pathogenic protozoa infections. Bacitracin inhibits cell wall biosynthesis and permeability through binding to the undecaprenyl pyrophosphate. Bacitracin inhibits macromolecular synthesis. Bacitracin is also a protein disulfide isomerase (PDI) inhibitor[1][2][3].
In Vitro: Bacitracin (64 μg/mL, 24 h) together with Colistin shows antibacterial activity against S. aureus BA01611[1].
Bacitracin (64 μg/mL, 1 or 2 h) damages the cell surface to grape-like cell clusters, and the cell boundaries are faint and unclear[1].
In Vivo: Bacitracin (0-100 mg/kg, intramuscular injection, daily for 12 consecutive days) shows anti-tumor efficacy in HCC model[3].
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