Neomycin (sulfate)
CAS No. : 1405-10-3
| Size | Price | Stock |
|---|---|---|
| 500mg | $30 | In-stock |
| 1g | $35 | In-stock |
| 5g | $52 | In-stock |
| 10g | $60 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-B0470 |
| M.Wt: | 908.88 |
| Formula: | C23H52N6O25S3 |
| Purity: | >98 % |
| Solubility: | H2O : 250 mg/mL (ultrasonic);DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) |
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis[1][2]. In Vitro: Neomycin is effective against most gram-negative organisms except Pseudomonas aeruginosa and anaerobic bacteria. Its activity against gram-positive microorganisms is more or less limited to staphylococci, but bacterial resistance supervenes after prolonged use[1].
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