IDO-IN-7


CAS No. : 1402836-58-1

(Synonyms: NLG-919 analogue; GDC-0919 analogue)

1402836-58-1
Price and Availability of CAS No. : 1402836-58-1
Size Price Stock
5mg $30 In-stock
10mg $50 In-stock
25mg $90 In-stock
50mg $150 In-stock
100mg $250 In-stock
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Cat. No. : HY-13983
M.Wt: 282.38
Formula: C18H22N2O
Purity: >98 %
Solubility: Ethanol : 25 mg/mL (ultrasonic);DMSO : 50 mg/mL (ultrasonic)
Introduction of 1402836-58-1 :

IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM. IC50 & Target: IC50: 38 nM (IDO1)[1] In Vitro: IDO-IN-7 (NLG-919 analogue) is a potent IDO1 inhibitor (IC50=38 nM). The binding mode of IDO-IN-7 to IDO1 is experimentally available and shows a direct coordinative interaction to the sixth coordination site of ferric heme. IDO-IN-7 has been used as reference compound in other studies to validate high-throughput screening assay for IDO1 inhibition and develop immunostimulatory nanomicellar carrier[1].

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