GV-58
CAS No. : 1402821-41-3
| Size | Price | Stock |
|---|---|---|
| 1mg | $60 | In-stock |
| 5mg | $180 | In-stock |
| 10mg | $280 | In-stock |
| 25mg | $550 | In-stock |
| 50mg | $780 | In-stock |
| 100mg | $1100 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12498 |
| M.Wt: | 374.50 |
| Formula: | C18H26N6OS |
| Purity: | >98 % |
| Solubility: | DMSO : 75 mg/mL (ultrasonic) |
GV-58 is a novel N- and P/Q-type calcium (Ca2+) channel agonist with EC50s of 7.21 and 8.81 μM, respectively. GV-58 slows the deactivation of channels, resulting in a large increase in presynaptic Ca2+ entry during activity. GV-58 can be used in lambert-eaton myasthenic syndrome (LEMS) research[1][2][3]. In Vitro:GV-58 (50 μM; 30 min) restores function in LEMS passive transfer neuromuscular junction[1].
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