Ca2+ channel agonist 1
CAS No. : 1402821-24-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $200 | In-stock |
| 5mg | $420 | In-stock |
| 10mg | $600 | In-stock |
| 50mg | $1800 | In-stock |
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| Cat. No. : | HY-41076 |
| M.Wt: | 354.45 |
| Formula: | C19H26N6O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction. IC50 & Target: EC50: 14.23 μM (N-type Ca2+ channel), 3.34 μM (Cdk2)[1] In Vitro: Ca2+ channel agonist 1 (Compound 13d) is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively. Ca2+ channel agonist 1 exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine[1].
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