BAN ORL 24
CAS No. : 1401463-54-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $101 | In-stock |
| 10 mg | Get quote | |
| 50 mg | Get quote | |
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| Cat. No. : | HY-13222 |
| M.Wt: | 506.51 |
| Formula: | C27H37Cl2N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 200 mg/mL (ultrasonic);H2O : 100 mg/mL (ultrasonic) |
BAN ORL 24 is a nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) antagonist. BAN ORL 24 has antagonistic effect for nociceptin (NOP) receptor with KI value of 0.24 nM in CHO cell. BAN ORL 24 can be used for the research of cancer and analgesic[1].
IC50 & Target:Ki: 0.24 nM (NOP in CHO cell)[1].
IC50: 50 μM (NOR); 0.224 μM (MOR)[2]
In Vitro: BAN ORL 24 has antagonist for NOR and MOR (opioid receptor subtype) with IC50 values of 50 μM and 0.224 μM, respectively[2].
In Vivo: BAN ORL 24 (10 mg/kg; i.v.) attenuates the duration of BPRIM97 thermal antinociception[3].
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