ML277
CAS No. : 1401242-74-7
(Synonyms: CID-53347902)
| Size | Price | Stock |
|---|---|---|
| 5mg | $96 | In-stock |
| 10mg | $144 | In-stock |
| 25mg | $260 | In-stock |
| 50mg | $390 | In-stock |
| 100mg | $585 | In-stock |
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| Cat. No. : | HY-12343 |
| M.Wt: | 471.59 |
| Formula: | C23H25N3O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 56 mg/mL |
ML277 (CID-53347902) is a potent and selective activator of K(v)7.1 (KCNQ1) potassium channel activator (EC50=270 nM), rescues function of pathophysiologically important mutant channel complexes in human induced pluripotent stem cell-derived cardiomyocytes[1][2].
In Vitro:ML277 (1 μM) increases the amplitude of KCNQ1 whole-cell and single-channel currents[1].
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