| Size | Price | Stock |
|---|---|---|
| 2mg | $50 | In-stock |
| 5mg | $95 | In-stock |
| 10mg | $175 | In-stock |
| 25mg | $310 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $630 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-16743 |
| M.Wt: | 389.49 |
| Formula: | C20H24FN3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Ibiglustat (Venglustat) is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease[1][2]. IC50 & Target: Glucosylceramide synthase[1]. In Vitro: Ibiglustat (SAR402671) (1 μM, 15 days; Fabry disease (FD) cells) is close to the physiological level in untreated WT cells in GL-3 levels, suggesting that Ibiglustat can prevent additional GL-3 accumulation and could serve to ameliorate the abundant levels of this sphingolipid in FD cardiomyocytes[4]
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