Tylosin
CAS No. : 1401-69-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $28 | In-stock |
| 10mg | $40 | In-stock |
| 50mg | $79 | In-stock |
| 100mg | $90 | In-stock |
| 500mg | $225 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-B0519A |
| M.Wt: | 916.10 |
| Formula: | C46H77NO17 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : < 0.1 mg/mL |
Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle[1][2][3].
IC50 & Target:Antibiotic[1]
In Vitro: Tylosin exerts antibacterial effects by binding to 23S rRNA of the bacterial ribosomal 50S subunit [1].
Tylosin also prevents growth of Gram-negative strains, with MICs of 64 μg/mL, 32 μg/mL, 512 μg/mL and 1 μg/mL for M. haemolytica 11935, P. multocida 4407, E. coli ATCC 25922 and E. coli AS19rlmAI, respectively[3].
In Vivo: Tylosin (10-500 mg/kg; s.c.) generally suppresses the elevated TNF-α and IL-1β levels and increases the IL-10 levels in the Lipopolysaccharide (LPS) -treated animals[4].
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