Tannic acid
CAS No. : 1401-55-4
| Size | Price | Stock |
|---|---|---|
| 500mg | $30 | In-stock |
| 1g | $40 | In-stock |
| 5g | $60 | In-stock |
| 10g | $75 | In-stock |
| 50g | $120 | In-stock |
| 100g | $156 | In-stock |
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| 500 g | Get quote | |
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| Cat. No. : | HY-B2136 |
| M.Wt: | 1701.20 |
| Formula: | C76H52O46 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Tannic acid is a novel hERG channel blocker with IC50 of 3.4 μM. IC50 & Target:IC50: 3.4 μM (hERG channel)[1] In Vivo: During the course of treatment, tannic acid significantly ameliorates these phenotypes in AD skin lesions. Tannic acid treatment aslo reduces these dermal changes compare with AD mice. Treatment with tannic acid increases PPARγ expression in AD skin sections. The PPARγ protein expression is suppressed in vehicle-treated AD mice, but when treats with tannic acid, its expression is increased dramatically. The IL-1β, TNFα, TNFR1, and COX2 protein expressions are significantly up-regulated in vehicle-treated AD mice, but significantly suppressed by tannic acid treatment[2].
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