DBCO-Sulfo-NHS ester (sodium)
CAS No. : 1400191-52-7
| Size | Price | Stock |
|---|---|---|
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| Cat. No. : | HY-123687 |
| M.Wt: | 532.50 |
| Formula: | C25H21N2NaO8S |
| Purity: | >98 % |
| Solubility: | H2O : ≥ 50 mg/mL |
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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