Metiazinic acid
CAS No. : 13993-65-2
(Synonyms: 16091 RP)
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| Cat. No. : | HY-120714 |
| M.Wt: | 271.33 |
| Formula: | C15H13NO2S |
| Purity: | >98 % |
| Solubility: |
Metiazinic acid (16091 RP) is an orally active and brain-penetrant phenothiazine derivative and a non-steroidal anti-inflammatory drug (NSAID). Metiazinic acid can be used for the research of inflammatory conditions[1].
In Vivo:Metiazinic acid (20 mg/kg; p.o.; single dose) accumulates in Carrageenan (HY-125474)-induced edematous paw tissue at levels higher than non-inflamed control tissue[1].
Metiazinic acid (20 mg/kg; p.o.; single dose) accumulates in ultraviolet light-induced erythematous skin at levels higher than non-inflamed control skin[1].
Metiazinic acid (20 mg/kg; p.o.; single dose) distributes to multiple tissues in healthy rats and healthy rabbits[1].
Metiazinic acid (20-60 mg/kg; p.o.; single dose) is rapidly absorbed, distributed primarily to the kidneys, and excreted mainly via urine in healthy rabbits[1].
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