PSB-1737
CAS No. : 139896-80-3
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| Cat. No. : | HY-125313 |
| M.Wt: | 325.32 |
| Formula: | C18H15NO5 |
| Purity: | >98 % |
| Solubility: |
PSB-1737 is a human-selective GPR17 agonist with an EC50 for human GPR17 of 270 nM, and its activity on murine GPR17 is relatively weak (EC50 > 10 μM). PSB-1737 shows no significant inhibition at the glycine binding site of NMDA receptors, and has no significant agonistic or antagonistic activity on P2Y receptor subtypes. PSB-1737 can be used in demyelinating diseases (such as multiple sclerosis) or inflammatory-related anemia[1].
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