D-threo-PPMP (hydrochloride)
CAS No. : 139889-65-9
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| Cat. No. : | HY-116535 |
| M.Wt: | 511.18 |
| Formula: | C29H51ClN2O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
D-threo-PPMP hydrochloride is a potent inhibitor of glucosylceramide (GlcCer) synthase. D-threo-PPMP hydrochloride can block karyokinesis and reduce cyst production[1][2]. IC50 & Target: glucosylceramide synthase[1] In Vitro: D-threo-PPMP (10 μM; 72 h) hydrochloride decreases the MDR1 expression by 70% in KB-V0.01 cells[1].
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