DBCO-Maleimide


CAS No. : 1395786-30-7

1395786-30-7
Price and Availability of CAS No. : 1395786-30-7
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50mg $266 In-stock
100mg $316 In-stock
250mg $667 In-stock
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Cat. No. : HY-116270
M.Wt: 427.45
Formula: C25H21N3O4
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 1395786-30-7 :

DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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