PF-06291874


CAS No. : 1393124-08-7

(Synonyms: Glucagon receptor antagonists-4)

1393124-08-7
Price and Availability of CAS No. : 1393124-08-7
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5mg $70 In-stock
10mg $100 In-stock
25mg $220 In-stock
50mg $390 In-stock
100mg $680 In-stock
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Cat. No. : HY-19947
M.Wt: 503.51
Formula: C26H28F3N3O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1393124-08-7 :

PF-06291874 is a highly potent, non-peptide and orally active glucagon receptor antagonist. PF-06291874 is under the study for type 2 diabetes mellitus (T2DM)[1][2]. In Vivo: PF-06291874 exposure is approximately dose-proportional with a half-life of ∼19.7-22.7 h. PF-06291874 has a fast on and off rate. PF-06291874 is highly bound to human plasma protein, with a mean free fraction of ∼0.55%[3].

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