SI-113
CAS No. : 1392816-46-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $175 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $472 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-117357 |
| M.Wt: | 400.48 |
| Formula: | C23H24N6O |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
SI-113 is a SGK1 inhibitor, with an IC50 of 600 nM. SI113 induces autophagy[1][2].
In Vitro:SI-113 exhibits IC50 values of 10.5, 14.4 and 10.7 μM in GIN8, GIN28 and GCE28 GBM cells[1].
SI-113 induces significant increases in caspase-3/7 activation in all GBM cell lines[1].
SI-113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells[2].
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