MRL-871
CAS No. : 1392809-08-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $290 | In-stock |
| 10mg | $480 | In-stock |
| 25mg | $960 | In-stock |
| 50mg | $1550 | In-stock |
| 100mg | $2480 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-119464 |
| M.Wt: | 444.79 |
| Formula: | C22H12ClF3N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells[1]. In Vitro: MRL-871 (compound 3; 10 μM, 24h) significantly reduces IL-17a mRNA expression 48-fold in EL4 cells[1].
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