Fmoc-Lys-OH (hydrochloride)
CAS No. : 139262-23-0
| Size | Price | Stock |
|---|---|---|
| 1g | $10 | In-stock |
| 5g | $15 | In-stock |
| 10g | $27 | In-stock |
| 25g | $33 | In-stock |
| 100g | $96 | In-stock |
| 500g | $479 | In-stock |
| 1000g | $790 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-W010975 |
| M.Wt: | 404.89 |
| Formula: | C21H25ClN2O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Fmoc-Lys-OH hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Lys-OH hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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