N-Boc-PEG5-bromide
CAS No. : 1392499-32-9
| Size | Price | Stock |
|---|---|---|
| 100mg | $22 | In-stock |
| 250mg | $27 | In-stock |
| 1g | $57 | In-stock |
| 5g | $238 | In-stock |
| 10g | $425 | In-stock |
| 25g | $850 | In-stock |
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| 100 g | Get quote | |
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| Cat. No. : | HY-120702 |
| M.Wt: | 400.31 |
| Formula: | C15H30BrNO6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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