GSK3532795


CAS No. : 1392312-45-6

(Synonyms: BMS-955176)

1392312-45-6
Price and Availability of CAS No. : 1392312-45-6
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Cat. No. : HY-112714
M.Wt: 691.02
Formula: C42H62N2O4S
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1392312-45-6 :

GSK3532795 (BMS-955176) is a potent, orally active, second-generation HIV-1 maturation inhibitor, with EC50s of 1.9, 10.2, 2.7 and 13 nM for HIV-1 WT, HIV-1 WT(human serum), HIV-1 V370A, and HIV-1 ΔV370, respectively[1]. IC50 & Target: EC50: 1.9 nM (HIV-1 WT), 10.2 nM (HIV-1 WT(human serum)), 2.7 nM (HIV-1 V370A), 13 nM (HIV-1 ΔV370)[1] In Vitro: GSK3532795 exhibits Kds of 3.2 ± 0.6, 4.3 ± 2.0, 6.5 ± 2.2 and 33.6 ± 5.9 nM for HIV WT, HIV V362I, HIV V370A, HIV ΔV370, respectively[1].

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