Leucomycin


CAS No. : 1392-21-8

(Synonyms: Kitasamycin)

1392-21-8
Price and Availability of CAS No. : 1392-21-8
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50mg $25 In-stock
100mg $35 In-stock
200mg $56 In-stock
500mg $100 In-stock
1g $150 In-stock
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Cat. No. : HY-N7112
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: H2O : < 0.1 mg/mL;DMSO : 110 mg/mL (ultrasonic)
Introduction of 1392-21-8 :

Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses[1][2][3][4][5][6][7]. In Vitro:Leucomycin (0.1-100 μg/mL, 0-8 h) demonstrates weak bactericidal activities against Staphylococci similar to Maridomycin in vitro[6].

Antibacterial spectra of Leucomycin[6]
Organism Staphylococcus aureus FDA209 P Streptococcuspyogenes E-14 Streptococcus viridans Diplococcus pneumoniae type I Corynebacterium diphtheriae Bacillus subtilis Neisseria gonorrhoeae
MIC in μg/mL1.56 0.78 0.39 0.39 0.39 1.56 0.78
In Vivo:Leucomycin ( 29.8-446 mg/kg, s.c., i.p., i.v., p.o., a single dose for 7 days) has therapeutic activities on S. aureus 308 A-1, S. pyogenes E-14 and D. pneumoniae type I infection in mice[6].

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