Bosutinib isomer
CAS No. : 1391063-17-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $500 | In-stock |
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| Cat. No. : | HY-103029 |
| M.Wt: | 530.45 |
| Formula: | C26H29Cl2N5O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1]. In Vitro:Bosutinib isomer (0-10 μM) shows the high growth inhibitory potential against HEK293T, MM1.S, and MDA-MB-231 cells, with IC50 values of 1.6 ± 0.19, 3.9 ± 0.50, and 1.8 ± 0.061 μM, respectively[1].
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