Octocog alfa
CAS No. : 139076-62-3
(Synonyms: ADVATE; BAY 81-8973; Kovaltry)
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| Cat. No. : | HY-112865 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Octocog alfa (ADVATE; BAY 81-8973; Kovaltry) is a standard half-length recombinant coagulation factor FVIII replacement therapy that also functions as a thrombin generation modulator. Octocog alfa regulates thrombin generation-related parameters in vitro and is used in studies related to severe hemophilia A[1][2][3]. In Vivo:At a single dose of 50 IU/kg, octocog alfa maintains the average FVIII activity level above 40 IU/dL for less than 1 day, above 10 IU/dL for less than 2 days, and causes no significant changes in coagulation biomarker levels before and after infusion[2].
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