Anemarsaponin B


CAS No. : 139051-27-7

139051-27-7
Price and Availability of CAS No. : 139051-27-7
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1mg $114 In-stock
5mg $250 In-stock
10mg $375 In-stock
25mg $675 In-stock
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Cat. No. : HY-N0811
M.Wt: 903.06
Formula: C45H74O18
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 139051-27-7 :

Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect [1].

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