JMV 449


CAS No. : 139026-66-7

139026-66-7
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Cat. No. : HY-P1256
M.Wt: 746.98
Formula: C38H66N8O7
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 139026-66-7 :

JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC50 of 0.15 nM for inhibition of [125I]-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse[1][2]. In Vivo: JMV 449 (120 pmol/mouse; i.c.v) shows analgesic effect[2].

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