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|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-P1256 |
| M.Wt: | 746.98 |
| Formula: | C38H66N8O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
JMV 449 is a potent neurotensin receptor agonist. JMV 449 shows an IC50 of 0.15 nM for inhibition of [125I]-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. JMV 449 has highly potent and long-lasting hypothermic and analgesic effects in the mouse[1][2]. In Vivo: JMV 449 (120 pmol/mouse; i.c.v) shows analgesic effect[2].
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