Ziprasidone (hydrochloride monohydrate)


CAS No. : 138982-67-9

(Synonyms: CP 88059 (hydrochloride monohydrate))

138982-67-9
Price and Availability of CAS No. : 138982-67-9
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10mg $61 In-stock
25mg $103 In-stock
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100mg $255 In-stock
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Cat. No. : HY-17407
M.Wt: 467.41
Formula: C21H24Cl2N4O2S
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 138982-67-9 :

Ziprasidone (CP-88059) hydrochloride monohydrate is an orally active combined 5-HT and dopamine receptor antagonist[1]. Ziprasidone hydrochloride monohydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM)[1]. In Vitro:Ziprasidone hydrochloride monohydrate (0-500 nM, 150 seconds) blocks wild-type hERG current[2]. In Vivo:Ziprasidone hydrochloride monohydrate (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold[3].

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