CAS No. : 138982-67-9
(Synonyms: CP 88059 (hydrochloride monohydrate))
| Size | Price | Stock |
|---|---|---|
| 5mg | $39 | In-stock |
| 10mg | $61 | In-stock |
| 25mg | $103 | In-stock |
| 50mg | $155 | In-stock |
| 100mg | $255 | In-stock |
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| Cat. No. : | HY-17407 |
| M.Wt: | 467.41 |
| Formula: | C21H24Cl2N4O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Ziprasidone (CP-88059) hydrochloride monohydrate is an orally active combined 5-HT and dopamine receptor antagonist[1]. Ziprasidone hydrochloride monohydrate has affinities for Rat D2 (Ki=4.8 nM), 5-HT2A (Ki=0.42 nM) and 5-HT1A (Ki=3.4 nM)[1]. In Vitro:Ziprasidone hydrochloride monohydrate (0-500 nM, 150 seconds) blocks wild-type hERG current[2]. In Vivo:Ziprasidone hydrochloride monohydrate (oral gavage; 20 mg/kg; once daily; 7 weeks) results in weight loss, low level physical activity, high resting energy expenditure and greater capacity for thermogenesis when subjected to cold[3].
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