ND-2110
CAS No. : 1388894-17-4
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| Cat. No. : | HY-117622 |
| M.Wt: | 416.54 |
| Formula: | C21H28N4O3S |
| Purity: | >98 % |
| Solubility: |
ND-2110 is a selective IRAK4 inhibitor (Ki: 7.5 nM). ND-2110 binds to the ATP pocket of IRAK4. ND-2110 targets the subset of activated B cell-like (ABC) subtype of diffuse large B cell lymphoma (DLBCL) cell lines with MYD88 L265P mutations,. ND-2110 inhibits LPS-induced TNF production, alleviates collagen-induced arthritis, and blocks gout formation in mouse models[1].
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