OVA Peptide(257-264)


CAS No. : 138831-86-4

138831-86-4
Price and Availability of CAS No. : 138831-86-4
Size Price Stock
1mg $90 In-stock
5mg $170 In-stock
10mg $270 In-stock
25mg $460 In-stock
50mg $662 In-stock
100mg $945 In-stock
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500 mg Get quote
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Cat. No. : HY-P1489
M.Wt: 963.13
Formula: C45H74N10O13
Purity: >98 %
Solubility: DMSO : 40 mg/mL (ultrasonic;adjust pH to 3 with 1 M HCL);0.1% TFA in Water : 1.83 mg/mL (ultrasonic)
Introduction of 138831-86-4 :

OVA Peptide(257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide can be from ovalbumin presented by the class I MHC molecule, H-2Kb. In Vitro:TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide(257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide(257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide(257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide(257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1].

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