Sardomozide dihydrochloride
CAS No. : 138794-73-7
(Synonyms: CGP 48664A)
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $320 | In-stock |
| 50mg | $512 | In-stock |
| 100mg | $820 | In-stock |
| 1g | $2900 | In-stock |
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| Cat. No. : | HY-13746B |
| M.Wt: | 303.19 |
| Formula: | C11H16Cl2N6 |
| Purity: | >98 % |
| Solubility: | DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 3.85 mg/mL (ultrasonic;warming;heat to 60°C) |
Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM. IC50 & Target: IC50: 5 nM (SAMDC)[1] In Vitro: Sardomozide is a S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM in cell assay. Following treatment for 48 h with 3 μM Sardomozide, intracellular SAMDC activity is reduced to 10% of control[1]. When the CHO/664 cells are grown in the presence of Sardomozide and during treatment with DENSPM, vacuole formation is not observed, and these cells are growth-inhibited and contain levels of DENSPM similar to the parental CHO cells[2].
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