Icatibant (acetate)
CAS No. : 138614-30-9
(Synonyms: HOE 140 (acetate))
| Size | Price | Stock |
|---|---|---|
| 1mg | $80 | In-stock |
| 5mg | $240 | In-stock |
| 10mg | $380 | In-stock |
| 25mg | $680 | In-stock |
| 50mg | $1020 | In-stock |
| 100mg | $1530 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-108896 |
| M.Wt: | 1364.57 |
| Formula: | C61H93N19O15S |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively[1][2][3]. In Vivo: Icatibant (10-30 μM) potentiates angiotensin III, but not angiotensin II (contraction mediated by angiotensin AT1 receptors), and Lys-des-Arg9-bradykinin, but not des-Arg9-bradykinin (effects mediated by the bradykinin B1 receptors)[3].
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