DBCO-NHS ester 2
CAS No. : 1384870-47-6
| Size | Price | Stock |
|---|---|---|
| 100mg | $110 | In-stock |
| 250mg | $212 | In-stock |
| 1g | $623 | In-stock |
| 5g | $2233 | In-stock |
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| Cat. No. : | HY-115524 |
| M.Wt: | 430.45 |
| Formula: | C25H22N2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 14.29 mg/mL (ultrasonic) |
DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. In Vitro: ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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