ML289


CAS No. : 1382481-79-9

(Synonyms: VU0463597)

1382481-79-9
Price and Availability of CAS No. : 1382481-79-9
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5mg $90 In-stock
10mg $150 In-stock
25mg $300 In-stock
50mg $480 In-stock
100mg $750 In-stock
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Cat. No. : HY-19630
M.Wt: 349.42
Formula: C22H23NO3
Purity: >98 %
Solubility:
Introduction of 1382481-79-9 :

ML289 (VU0463597) is a potent, selective, and CNS-penetrant mGlu3 (IC50=0.66 μM) negative allosteric modulator. ML289 displays >15-fold selectivity over mGlu2 and is inactive against mGlu5[1]. ML289 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: ML289 (VU0463597) is a CNS-penetrant, metabotropic glutamate receptor 3 (mGlu3) negative allosteric modulator probe[1].

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