Z-VRPR-FMK
CAS No. : 1381885-28-4
| Size | Price | Stock |
|---|---|---|
| 100μg | $251 | Get quote |
| 200μg | $400 | Get quote |
| 500μg | $750 | Get quote |
| 1mg | $1280 | In-stock |
| 5mg | $3000 | In-stock |
| 10mg | $4500 | In-stock |
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| Cat. No. : | HY-120231 |
| M.Wt: | 676.78 |
| Formula: | C31H49FN10O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression[1][2].
In Vitro:Z-VRPR-FMK (50 μM, 24 h) can effectively reduce the level of c-REL in the nucleus of HBL-1 cells and inhibit the signal transduction of NF-κB[2].
Z-VRPR-FMK (50 μM, 48 h) can inhibit the proliferation of ABC-DLBCL cell lines HBL-1, TMD8, OCI-Ly3 and OCI-Ly10[2].
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