RC-3095
CAS No. : 138147-78-1
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| Cat. No. : | HY-P0107 |
| M.Wt: | 1106.32 |
| Formula: | C56H79N15O9 |
| Purity: | >98 % |
| Solubility: | H2O |
RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist[1]. RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2].
IC50 & Target: Bombesin receptor; GRPR[1]
In Vivo: RC-3095 impairs aversive but not recognition memory in Wistar male rats[1].
RC-3095 (0.3 mg/kg or 1 mg/kg; S.C.) shows anti-inflammatory effects in 2 experimental models of arthritis, collagen-induced arthritis (CIA) and antigen-induced arthritis (AIA)[2].
Arthritic mice treated with RC-3095 show a significant reduction in the concentrations of IL-17, IL-1 , and TNF, and showed a diminished expression of GRPR[2].
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