T2AA
CAS No. : 1380782-27-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $175 | In-stock |
| 25mg | $370 | In-stock |
| 50mg | $590 | In-stock |
| 100mg | $940 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-110111 |
| M.Wt: | 511.09 |
| Formula: | C15H15I2NO3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
T2AA is a monoubiquitinated proliferating cell nuclear antigen (PCNA) inhibitor that prevents DNA repair, increases double-strand break (DSB) formation and promotes necroptosis and cell cycle arrest in G1 phase[1].
In Vitro:T2AA (15 μM, 72 h) inhibits interstrand DNA crosslink (ICL) repair, it can prevent the disassembly of DNA double-strand break (DSB) formed as an ICL repair intermediate, and has the ability to inhibit DSB repair[1].
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