JMS-17-2


CAS No. : 1380392-05-1

1380392-05-1
Price and Availability of CAS No. : 1380392-05-1
Size Price Stock
5mg $99 In-stock
10mg $165 In-stock
25mg $295 In-stock
50mg $440 In-stock
100mg $620 In-stock
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500 mg Get quote
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Cat. No. : HY-123918
M.Wt: 419.95
Formula: C25H26ClN3O
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 1380392-05-1 :

JMS-17-2 is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 impairs metastatic seeding and colonization of breast cancer cells[1]. IC50 & Target:IC50: 0.32 nM (CX3CR1)[1] In Vivo: JMS-17-2 (10 mg/kg; aministered i.p.; twice a day for three weeks) causes a dramatic reduction of tumors in both skeleton and visceral organs in SCID mice[1].

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