Trimethobenzamide
CAS No. : 138-56-7
(Synonyms: Ro 2-9578 (free base))
| Size | Price | Stock |
|---|---|---|
| 25mg | $46 | Get quote |
| 50mg | $73 | Get quote |
| 100mg | $116 | Get quote |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12751 |
| M.Wt: | 388.46 |
| Formula: | C21H28N2O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Trimethobenzamide (Ro 2-9578 free base) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting[1]. IC50 & Target: D2 receptor[1] In Vitro: Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center[1]. In Vivo: The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration[1].
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