| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $90 | In-stock |
| 25mg | $200 | In-stock |
| 50mg | $338 | In-stock |
| 100mg | $585 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-19971 |
| M.Wt: | 346.60 |
| Formula: | C13H10Cl3N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
ML239 is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM. In Vitro: ML239 (Compound 7j) is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM, with ∼24-fold selectivity against the control cell line[1]. ML239 inhibits breast cancer stem-like cells, most likely through activation of fatty acid desaturase 2 (FADS2). ML239 is cytotoxic to NCIH661 cells, and FADS2 knockdown reduces ML239 cytotoxicity, and furthermore, FADS2 inhibitor SC-26196 also reduces ML239 cytotoxicity in cancer cell lines (CCLs)[2].
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