Macozinone
CAS No. : 1377239-83-2
(Synonyms: PBTZ169)
| Size | Price | Stock |
|---|---|---|
| 5mg | $52 | In-stock |
| 10mg | $82 | In-stock |
| 25mg | $165 | In-stock |
| 50mg | $265 | In-stock |
| 100mg | $420 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-12903 |
| M.Wt: | 456.48 |
| Formula: | C20H23F3N4O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 6.4 mg/mL (ultrasonic) |
Macozinone (PBTZ169) is a bactericidal benzothiazinone and a potent DprE1 (decaprenylphosphoryl-β-d-ribose 2′-oxidase) inhibitor. Macozinone inhibits the essential flavoprotein DprE1 by forming a covalent bond with the active-site Cys387 residue. Macozinone has antituberculosis effect[1][2]. IC50 & Target: DprE1[1] In Vitro: Macozinone (PBTZ169) is highly potent against M. tuberculosis in vitro, ex vivo, and in vivo[2].
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