Velpatasvir
CAS No. : 1377049-84-7
(Synonyms: GS-5816)
| Size | Price | Stock |
|---|---|---|
| 5mg | $38 | In-stock |
| 10mg | $60 | In-stock |
| 50mg | $140 | In-stock |
| 100mg | $200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12530 |
| M.Wt: | 883.00 |
| Formula: | C49H54N8O8 |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic;warming);DMSO : ≥ 100 mg/mL |
Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 2.16 μM[2].
In Vivo: Velpatasvir (10 mg/kg/d, p.o.) alone or in combination with Sofosbuvir (HY-15005) (20 mg/kg/d) inhibits liver fibrosis in the CCl4-induced non-HCV rat model[3].
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