BMS-955829


CAS No. : 1375751-08-8

1375751-08-8
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Cat. No. : HY-120641
M.Wt: 376.36
Formula: C22H14F2N2O2
Purity: >98 %
Solubility:
Introduction of 1375751-08-8 :

BMS-955829 is an orally active and selective mGluR5 positive allosteric modulator with an EC50 of 2.6 nM. BMS-955829 has no intrinsic agonist activity and a low glutamate fold shift (2.4). BMS-955829 can effectively improve cognitive and executive function deficits in rodents. BMS-955829 can be used in the research of cognitive impairment diseases such as schizophrenia[1].

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