Poricoic acid B
CAS No. : 137551-39-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $175 | In-stock |
| 10mg | $280 | In-stock |
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| Cat. No. : | HY-N4124 |
| M.Wt: | 484.67 |
| Formula: | C30H44O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Poricoic acid B is a triterpenoid compound that can be isolated from Poria cocos. Poricoic acid B inhibits intracellular lipid accumulation and reduces the levels of hepatocyte injury markers. Poricoic acid B inhibits the production of NO, TNF-α, IL-1β and IL-6, thereby exerting anti-inflammatory activity. Poricoic acid B can be used in the research of metabolic dysfunction-associated fatty liver disease and inflammatory diseases[1][2][3].
In Vitro:Poricoic acid B (25-100 μM; 24 h) inhibits lipid accumulation in fat emulsion-induced steatotic L-02 hepatocytes and reduces the levels of hepatocyte injury markers[1].
Poricoic acid B (0-40 μg/mL; 24 h) inhibits LPS (HY-D1056)-induced NO production in RAW 264.7 cells and reduces the secretion of proinflammatory cytokines TNF-α, IL-1β and IL-6 in the cells[3].
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