GNE0877
CAS No. : 1374828-69-9
| Size | Price | Stock |
|---|---|---|
| 2mg | $70 | In-stock |
| 5mg | $150 | In-stock |
| 10mg | $240 | In-stock |
| 25mg | $490 | In-stock |
| 50mg | $770 | In-stock |
| 100mg | $1250 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15796 |
| M.Wt: | 339.32 |
| Formula: | C14H16F3N7 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
GNE0877 is a highly selective, orally active and brain-penetrant LRRK2 inhibitor with an IC50 of 3 nM and a Ki of 0.7 nM. GNE0877 can be used for the research of neuroscience[1]. IC50 & Target:IC50: 3 nM (LRRK2)[1] In Vitro:GNE0877 (1 μM; 10-30 min) shows good cellular potency in human liver microsomes and hepatocytes[1]. In Vivo:GNE0877 (10 and 50 mg/kg; i.p. once) inhibits LRRK2 Ser1292 autophosphorylation[1].
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